Invitro Tewameter® VT 310
The Tewameter® VT 310 is a specialized probe designed for high-precision TEWL (transepidermal water loss) measurements directly on Franz diffusion cells. What sets the VT 310 apart is its unique construction that fully emulates the upper part of a Franz cell—the donor chamber. This allows the probe to be placed directly onto the membrane, exactly as it would sit on human skin, without the need for any additional adapters or modifications. No other TEWL probe on the market offers this level of compatibility, making the VT 310 the ideal choice for in vitro skin permeability and barrier function studies. The measured TEWL values are expressed in g/h/m², the globally accepted absolute unit used for skin research.
Additionally, the VT 310 can be used with an optional high-quality Teflon centerpiece. This accessory is precisely engineered to fit both the probe and the receptor chamber of the Franz cell without requiring any clamps or additional fixtures. In this configuration, while the setup offers great flexibility, the measured TEWL values must be interpreted as relative, since the distance between the probe sensor and membrane surface is altered.
This dual functionality makes the Tewameter® VT 310 highly versatile, supporting both absolute and relative TEWL measurements. It is an essential tool for laboratories and researchers conducting topical product testing, permeation studies, and skin barrier research in both academic and industrial settings.
Invitro Tewameter® VT 310
The Tewameter® Triple TM 330T is an advanced instrument designed for precise and efficient measurement of transepidermal water loss (TEWL). Featuring three independent probe heads, it allows simultaneous assessment of multiple skin sites or larger surface areas under identical environmental conditions. This innovative design ensures highly reproducible results and significantly reduces measurement time, making it ideal for comparative studies, product testing, and dermatological research.

Advantages of Tewameter® Triple TM 330T
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The three probe heads of the Tewameter® Triple TM 330T can be placed independently and flexibly on the skin—either close together or spaced apart—making setup quick and easy. This allows fast, reproducible measurement over a larger skin area.
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The software displays the TEWL value, average, and standard deviation for each head, along with an overall average.
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It also enables simultaneous measurement on three different skin sites (e.g., with different products) under identical environmental conditions.
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The included transport suitcase doubles as a calibration check unit. The TM 330T is compatible with all MPA systems.

Where to use:
The measurement of the TEWL and the quality of the barrier function of the skin is the basic measurement for all cosmetic applications:
• Indispensable instrument for formulation, claim support and efficacy & safety testing of skin care, household product, raw materials and pharmaceutical products
• Typical claims (example) with the Tewameter®: barrier improvement, regenerating, protecting, for sensitive skin, calming/soothing, vitalizing, nonoccluding, tolerable, anti-irritation, anti-pollution, etc.
• Sweat studies (antiperspirant efficacy)
• Patch Tests
• Standard in dermatological basic research on humans and animals.
• In occupational health the measurement of the skin barrier function can show the necessity of using skin protection products.
• Other industries, e.g. textile-, nutrition, packaging, paper/tissue are using this measurement.
• Local skin energy balance could be an exciting new parameter for different research fields: e.g. sports, nutrition & food supplements, textile, micro circulation, sleep medicine, special cooling products, etc.
Advantages of “Open Chamber” :