Visioline® VL 650 (Quantirides®)
Effortless Assessment of Skin Micro & Macro Relief
Where to use?
A Trusted Tool for Anti-Wrinkle Efficacy Testing
For decades, the evaluation of skin micro- and macro-relief has been a key focus in the cosmetic industry. The Visioline® VL 650 offers a precise, user-friendly, and cost-effective solution for R&D laboratories and testing institutes, making it ideal for formulation development and efficacy testing of anti-wrinkle products.
Specially designed to assess prominent wrinkles—such as crow’s feet and nasolabial folds—the Visioline® uses replica-based measurements, making it not only suitable for in-house testing but also highly effective in international ring studies.
Common claims substantiated with the Visioline® include:
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Anti-wrinkle
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Anti-aging
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Improvement of crow’s feet area
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Skin smoothing
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Rejuvenating effects
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Anti-roughness
With its robust methodology and reproducible results, the Visioline® is an essential tool for substantiating cosmetic claims with scientific precision.
How does Visioline® VL 650 work?
Proven Measurement Principle with Silflo® Replica Technology
The Visioline® VL 650 utilizes a skin replica-based analysis, employing Silflo®—a renowned white, non-glossy silicone material—to accurately capture the skin’s surface relief. The replica is illuminated inside the device using oblique lighting at a 35° angle, a method designed to cast shadows that emphasize surface irregularities.
These shadows, created by the elevated ridges in the replica that represent wrinkles, are then captured by a vertically mounted digital camera. The resulting images form the basis for precise, reproducible arithmetical evaluations, including:
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Wrinkle depth (μm)
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Wrinkle length (mm)
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Wrinkle area (mm²)
This robust and scientifically validated method ensures objective and quantitative wrinkle analysis.
Visioline® – before and after treatment
Replica Production Kit for Skin Relief Analysis
The Replica Kit provides all the necessary materials for creating high-quality skin surface impressions used in conjunction with the Visioline® VL 650 system. It is specially designed for accurate replication of both deep wrinkles (e.g., crow’s feet) and fine skin structures (e.g., inner forearm).
Kit Contents:
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225 g of Silflo® silicone material
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1 bottle of thinner
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1 bottle of catalyst
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100 double-sided adhesive rings
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100 stirring rods
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100 stirring cups
Silflo® offers the ideal viscosity for precise replication. It flows smoothly into both large and small wrinkles without distorting the natural skin surface and can be easily removed after curing.
📌 Storage Instructions:
Keep Silflo® in a cool, dry place, away from direct sunlight to maintain its quality and performance.
Advanced Software for Visioline® VL 650
The new-generation Visioline® software is powerful, user-friendly, and designed to streamline wrinkle and skin relief analysis with maximum precision and ease.
Study Manager: Centralized & Flexible
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Manage entire studies efficiently with the integrated Visioline® Study Manager
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Apply custom filters and analysis settings across all replicas in a study
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Define your own categories for wrinkle depth, length, and size—or use predefined settings
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Visual feedback: see color-coded results directly on the image for intuitive analysis
Smart Image Capturing
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Large, high-resolution live preview window
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Optimize replica positioning with the “matching score” for best contrast
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Use the “object overlay mask” to achieve maximum reproducibility between time points
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Replica check function ensures image quality before analysis
Accurate & Immediate Measurements
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Automatic, real-time display of wrinkle parameters:
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Depth (µm)
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Length (mm)
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Size (mm²)
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Individual wrinkle and overall image data, clearly color-coded
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Analyze single deep wrinkles in fine detail
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For micro-structure analysis:
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Full set of roughness indices R1–R5 (Ra–Rz equivalent)
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Topography volume
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Unfolded surface area (%)
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Includes “3D-like” visual animations—ideal for presentations, publications, and marketing
User-Friendly Calibration & Export
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Easy depth and length calibration via an illustrated, step-by-step menu
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Automatically generate a calibration report for your study documentation
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Fool-proof data and image export for use in reports or statistical software
License-Based Access
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One software license is included with each new Visioline® VL 650 device
Quick fact Visioline® VL 650
Visioline® combines compact hardware with intelligent, user-friendly software—a trusted solution for advanced wrinkle and skin structure analysis.
Compact & Convenient Hardware
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Lightweight, space-saving design
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Simple USB plug-and-play connection to your PC
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Multidirectional adjustment arm for precise replica placement
Reliable Replica-Based Measurement
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Uses Silflo®, a well-known white, non-glossy silicone for accurate skin relief replication
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Suitable for all body areas and wrinkle types, from crow’s feet to fine lines
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Easy and quick replica production in various sizes
Ideal for Global & Longitudinal Studies
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Replicas can be transported worldwide and centrally analyzed
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Perfect for multi-center and multi-ethnic studies
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Long-term storage without degradation, ideal for follow-up comparisons
Sophisticated Software Features
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Intuitive interface that simplifies complex data analysis
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Calculates established shadow measurement parameters:
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Wrinkle depth (μm)
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Wrinkle length (mm)
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Wrinkle area (mm²)
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Supports reproducible, quantitative efficacy evaluation
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Easy and accurate calibration of the system
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